Mathematical Simulation of the Cardiopulmonary System.
Final rept. 1 Oct 81-31 Aug 83,
TEXAS UNIV AT AUSTIN
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Multi-chamber, lumped parameter models of the pulmonary and circulatory systems have been developed which incorporate effects of whole-body accelerations WBA for any body orientation and a variety of breathing maneuvers. The pulmonary model has been used in an extensive study of effects of sustained WBA on pulmonary mechanics and ventilation. This study investigated the effectiveness of altering seat back angle to increase G-tolerance. The development and testing of the separate pulmonary and circulatory models has been reported in previous reports, as well as the above described WBA study. This final report describes latest efforts to incorporate feedback and control mechanisms in the circulatory mdoel to simulate the baroreceptor and chemoreceptor actions regulating blood flow and blood pressure in the human body. This work is not yet complete. Also described is a partially completed study using the pulmonary model to test and implement a non-invasive technique for diagnosing ventilation distribution dysfunctions. Author
- Anatomy and Physiology
- Numerical Mathematics
- Computer Hardware