Accession Number:

ADA135410

Title:

Lymphocyte Changes in Normal Apheresis Donors

Descriptive Note:

Master's thesis

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSONAFB OH

Personal Author(s):

Report Date:

1983-01-01

Pagination or Media Count:

86.0

Abstract:

Normal apheresis donors were studied to determine if any significant changes occur in the peripheral blood lymphocyte populations. Apheresis donors do have a significant reduction in the number of circulating B-cells following apheresis procedures. The long-term health effects of this B-lymphocyte loss is not known. No change in the ratio of helper to suppressor T-cells was observed when examined by monoclonal anti-human T-cell antibodies. Donor age and previous apheresis procedures did not appear to effect lymphocyte loss during apheresis. However, different apheresis instruments did show significant differences in the number of lymphocytes removed during normal apheresis procedures.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE