Mutagenic Potential of 4-Nitrophenyl Monochloromethyl (Phenyl) Phosphinate Using the Drosophila melanogaster Sex-Linked Recessive Lethal Test.
Final rept. 26 Jul-20 Dec 82,
LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
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4-Nitrophenyl monochloromethyl phenyl phosphinate TA009 is being considered as a prophylactic agent in anticholinesterase poisoning. It was tested for mutagenic activity using Drosophila melanogaster sex-linked recessive lethal assay. After 72-hour feeding exposures to 0.0100, 0.500, and 0.0075 mM, TA009 appeared non-mutagenic.