Accession Number:

ADA133974

Title:

Mutagenic Potential of 4-Nitrophenyl Monochloromethyl (Phenyl) Phosphinate Using the Drosophila melanogaster Sex-Linked Recessive Lethal Test.

Descriptive Note:

Final rept. 26 Jul-20 Dec 82,

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s):

Report Date:

1983-08-01

Pagination or Media Count:

30.0

Abstract:

4-Nitrophenyl monochloromethyl phenyl phosphinate TA009 is being considered as a prophylactic agent in anticholinesterase poisoning. It was tested for mutagenic activity using Drosophila melanogaster sex-linked recessive lethal assay. After 72-hour feeding exposures to 0.0100, 0.500, and 0.0075 mM, TA009 appeared non-mutagenic.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE