Accession Number:

ADA129524

Title:

Characterization of the Chemical Constitution and Profile of Pharmacological Activity of PGB(x).

Descriptive Note:

Final rept. 1 Jan 79-31 Dec 82,

Corporate Author:

OHIO STATE UNIV RESEARCH FOUNDATION COLUMBUS

Report Date:

1983-05-31

Pagination or Media Count:

52.0

Abstract:

The pharmacological studies conducted over the past four years have attempted to answer the following questions a Does PGBx produce organ level effects that are expressions of PGBxs established mitochondrial actions b Are the organ level effects related to PGBxs ability to act as a calcium iontophore c In assessing its potential therapeutic utility, are there other actions of PGBx that are relevant d Can an organ level bioassay be designed that is adapatble to the evaluation and comparison of biological activity of PGBx analogs and components The results of these studies are summarized.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE