Mediators of Fever and Muscle Proteolysis
ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
Pagination or Media Count:
The accelerated catabolism of skeletal-muscle protein that accompanies severe trauma or infection can now be ascribed to the actions of endogenously produced mediators. Two noteworthy studies described in this issue of the Journal have identified these actions by using in vitro preparations of rat skeletal muscle in a bioassay. Rates of proteolysis in muscle preparations were determined by measuring the release of free amino acid into the medium.