Accession Number:

ADA129183

Title:

Mutagenic Potential of 4-Nitrophenyl Methyl (Phenyl) Phosphinate Using the Drosophila melanogaster Sex-Linked Recessive Lethal Test.

Descriptive Note:

Final rept. 25 Jan-26 May 82,

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s):

Report Date:

1983-04-01

Pagination or Media Count:

31.0

Abstract:

4-Nitrophenyl methly phenyl phosphinate tw011 is being considered as a prophylactic agent in anticholinesterase poisoning. This compound was tested for mutagenic activity using Drosophila melanogaster Sex-Linked Recessive Lethal assay. It was found non-mutagenic after 72-hour feeding exposures to 0.002 and 0.0025 mM of tw011.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE