Mutagenic Potential of 4-Nitrophenyl Methyl (Phenyl) Phosphinate Using the Drosophila melanogaster Sex-Linked Recessive Lethal Test.
Final rept. 25 Jan-26 May 82,
LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
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4-Nitrophenyl methly phenyl phosphinate tw011 is being considered as a prophylactic agent in anticholinesterase poisoning. This compound was tested for mutagenic activity using Drosophila melanogaster Sex-Linked Recessive Lethal assay. It was found non-mutagenic after 72-hour feeding exposures to 0.002 and 0.0025 mM of tw011.