Quantitative Studies of Microembolization in Man during Surgical Trauma.
Annual rept. (Final), Aug 73-Mar 79,
BAYLOR COLL OF MEDICINE HOUSTON TX
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The present report describes recently completed studies of microembolization and alterations in platelet aggregation resulting from surgical trauma. A study of cyanotic congenital heart disease patients revealed an inverse relationship between the hematocrit and the mean size of platelet aggregates that could be induced in the patients blood in vitro by adenosine diphosphate. Another study observed the effects of changes in PaC02 on tissue oxygenation of patients under-going cardiopulmonary bypass while temperature, systemic blood flow and peripheral tissue oxygen delivery remained constant. Systemic oxygen consumption fell as the PC02 was increased from 35 to 40 mmHg, however, blood lactate remained constant and a metabolic adicosis did not develop. Author
- Medicine and Medical Research