Accession Number:

ADA126762

Title:

Mass Spectrometric Rapid Diagnosis of Infectious Diseases.

Descriptive Note:

Annual progress rept. no. 2, 1 Feb 79-31 Jan 80,

Corporate Author:

STATE UNIV OF NEW YORK AT BUFFALO SCHOOL OF MEDICINE

Report Date:

1980-01-01

Pagination or Media Count:

74.0

Abstract:

Using new chemical procedures, mass spectrometric instrumentation and appropriate computerized data analysis, the diagnosis of a number of infectious diseases, through the molecular weight profile of neutral metabolites urine, was demonstrated. Longitudinal studies on human volunteers infected with sandfly fever showed the appearance of a characteristic pattern prior to the onset of clinical symptoms which persisted some time after the symptoms have subsided. Tissue cultures infected with polio virus exhibited a characteristic pattern demonstratable within 5 hrs from infection.

Subject Categories:

  • Biochemistry
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE