Microbial Growth at Ultraslow Rates: Regulation and Genetic Stability.
Final rept. 1 Jan 76-31 Dec 82,
NEW HAMPSHIRE UNIV DURHAM DEPT OF MICROBIOLOGY
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A fermentor system has been developed to study bacterial growth from doubling times of 0.5 to 300 h. The studies show that specific growth rate mu, molar growth yield Y and nutrient levels cannot be related by any continuous mathematical expression. Instead, there are 3 growth rate ranges in bacterial growth containing 3 metabolic phases or domains -- exploitative, adaptive, and conservative -- which are sharply separated from each other by two gaps, or non-existent growth rate ranges, between doubling times of 15-20 h and between 80 and 125 h. Author