Accession Number:

ADA126299

Title:

Membrane Proteins of the Erythrocyte and Their Arrangement as a Function of Both in vitro and in vivo Aging.

Descriptive Note:

Final rept. 1 Mar 75-31 Jan 80,

Corporate Author:

SAINT JUDE CHILDREN'S RESEARCH HOSPITAL MEMPHIS TENN

Personal Author(s):

Report Date:

1980-07-01

Pagination or Media Count:

17.0

Abstract:

The changes as a result of aging of the normal human erythrocyte, with special emphasis on the membrane proteins, have been investigated to determine whether they are related to the age-dependent macrophage uptake of the red cell. Alterations in the metabolism can effect the arrangement of membrane proteins as evidenced by lectin agglutination of the red cells. Although serum proteins interact with the red cell, no alteration could be demonstrated in density-separated red cells. Author

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE