Accession Number:

ADA126138

Title:

Sensitivity of Some Tests for Alcohol Abuse: Findings in Nonalcoholics Recovering from Intoxication,

Descriptive Note:

Corporate Author:

FEDERAL AVIATION ADMINISTRATION WASHINGTON DC OFFICE OF AVIATION MEDICINE

Report Date:

1983-01-01

Pagination or Media Count:

21.0

Abstract:

A variety of measurements are sensitive to alcoholism some may be applicable to screening programs, but more precise knowledge of sensitivity and specificity would help to select a minimal test battery. This study assessed the sensitivity of some tests for alcoholism to a single drinking episode. Fifteen nonalcoholic men, 26-59 years old, participated. On one evening they drank ethonal, raising their blood alcohol concentrations BACs to 100-200 mgdl for at least 2h. At 0700 on the next morning, after 7 h of sleep, they ate breakfast, then completed a battery of performance tests. Blood samples were drawn at 0730 and 1130. The effects of alcohol, estimated by comparison of data with those obtained on another morning of the same week after an evening of abstinence, are summarized Heart rate, during sleep and all the next morning, was higher blood pressure, at 0700 and 1100, was unaffected. There was no effect on core body temperature, recorded hourly from 2400. The urinary excretion rates of catecholamines and ketogenic adrenal steroids were augmented by alcohol. The drug did not affect blood levels of gamma-glutamyl transpeptidase, glutamate oxaloacetate transaminase, high density lipid or total cholesterol, or uric acid. Performance tests affected by alcohol were number comparison, number addition, analysis of complex statements, and adaptability from an air traffic controller selection batter. Tests not affected were abstract reasoning, digit code, digit symbol, short-term memory, hand steadiness, pursuit tracking, rod-and-frame, and 100-hue color sorting.

Subject Categories:

  • Medicine and Medical Research
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE