Dermal Penetration and Distribution of 14C-Labeled N,N-Dipropylcyclohexane Carboxamide, AI3-36326 Study, May-October 1982. Phase 2.
ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD
Pagination or Media Count:
The candidate insect repellant N,N-dipropylcyclohexane carboxamide was assessed for absorption potential in rabbits and dogs by monitoring radiocarbon in excrets for 7 days following a single application. In both species, absorption occured primarily in the first 24 hours and measured 26 percent of the applied dose in rabbits and 12 percent in dogs through 7 days. No bioaccumulation in tissue specimens was noted at necropsy by this route. Absorption in man should be less than 10 percent of the applied dose. Author
- Stress Physiology