Accession Number:

ADA118818

Title:

Artificial Red Cells with Polyhemoglobin Membranes.

Descriptive Note:

Final rept. 1 Oct 80-30 Jun 81,

Corporate Author:

EXXON RESEARCH AND ENGINEERING CO LINDEN N J

Report Date:

1981-09-01

Pagination or Media Count:

43.0

Abstract:

Artificial red cells were prepared with polyhemoglobin membranes. Red-cell-size microdroplets containing 30 of hemoglobin were held in liquid membrane capsules and treated with glutaraldehyde that cross linked the hemoglobin at the surface of each microdroplet. A water-soluble surfactant was used to eject the cells from the oil and suspend them in saline. The hemoglobin was retained by the artificial red-cell membrane, but biotonometry revealed that it held oxygen more tenaceously after encapsulation. Author

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE