Mammalian Toxicology Testing: Problem Definition Study. Part 1. Comparative Analysis Report.
Final rept. 15 Dec 80-5 Apr 81,
LIFE SYSTEMS INC CLEVELAND OH
Pagination or Media Count:
Global Army mammalian toxicology testing requirements were defined, and to some extent those that would be the responsibility of the U.S. Army Medical Research and Development Command USAMRDC were identified. Since no quantitative or qualitative description of the Armys toxicology capability exists, the unmet requirements could not be precisely defined. Approaches for meeting a portion of the USAMRDCs unmet requirements were compared and particular emphasis was placed on production testing for mammalian toxicology studies. The cost to fulfill unmet requirements will approach 30 million per year for the global Army, and if it is assumed that 30 to 60 of the requirements are the responsibility of the medical organizations, their annual budgets would need to be increased by 10 to 20 million. Funding should not be diverted from other MRDC priority programs. Additional capability and capacity for toxicology testing should be added only after balancing and specifying requirements, resolving responsibilities and obtaining budgetary commitments.