Accession Number:

ADA109916

Title:

Transmission of Oropouche Virus from Man to Hamster by the Midge 'Culicoides Paraensis',

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH UNIT APO NEW YORK 09676*

Report Date:

1981-11-01

Pagination or Media Count:

15.0

Abstract:

Oropouche virus arbovirus family Bunyaviridae, Simbu serogroup was experimentally transmitted from man to hamster by the bite of Culicoides paraensis. Infection rates of 34 and 13 and transmission rates of 17 and 5 were observed after Culicoides engorged on patients with viremia levels of 6.3-7.3 and 5.3-6.2 log10 SMLD50ml of blood, respectively. Threshold titer necessary to enable infection or transmission by the midges was approximately 5.3 log 10 SMLD50ml of blood. Transmission was achieved 6 to 12 days after C. paraensis had taken the infective blood meal. This represents the first conclusive evidence of transmission of an arbovirus of public health importance to man by a member of the Ceratopogonidae family. Author

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE