Accession Number:

ADA107653

Title:

Equilibrium Performance Changes Produced by Atropine in M. mulatta and M. fascicularis.

Descriptive Note:

Final rept. Jun-Dec 80,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX

Report Date:

1981-09-01

Pagination or Media Count:

13.0

Abstract:

Two species of monkeys were trained to maintain a primate equilibrium platform in a relatively horizontal position by a control stick. Once asymptotic performance was achieved, animals received intramuscularly a saline control injection or 0.105, 0.140, 0.197, or 0.250 mgkg, in randomized order, of atropine sulfate. The animals performance was then observed for 3.5 hours. A statistically significant ordering of drug effects was seen, but no differences between species. Atropine produced no effect at the 0.105-mgkg dose, but marked performance decrements were measured after the 0.250-mgkg dose. Author

Subject Categories:

  • Stress Physiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE