Accession Number:

ADA102817

Title:

Candidiasis in the Burned Patient

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

1981-03-01

Pagination or Media Count:

3.0

Abstract:

Candida organisms were cultured from 452 or 1,513 hospitalized burned patients during a 6-year study period. Of the 172 patients with colonization of the eschar by this fungus, only 20.7 subsequently developed invasive candidal sepsis. The mortality of untreated Candida burn wound infection was 100, and with aggressive medical-surgical therapy, 91.6. Candidemia was present in 52 patients and 76.9 of these died. Candida infection was seen as a preterminal phenomenon, coincident with a generalized collapse of patients defensive and homeostatic mechanisms. For this reason, mortality was high and the infection rarely responded to treatment. Control of this lethal complication rests with prevention by the judicious use of intravenous broad-spectrum antibiotics and expeditious closure of the burn wound.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE