Evaluation of Selected Subacute Effects of the Nitrotoluene Group of Munitions Compounds on Fish and Potential Use in Aquatic Toxicity Evaluation.
Final rept. 1 Jan 80-31 Mar 81,
TULANE UNIV NEW ORLEANS LA SCHOOL OF PUBLIC HEALTH AND TROPICAL MEDICINE
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Juvenile bluegills were exposed to 0.05 mgL, 0.50 mgL, 1.0 mgL, 2.0 mgL, 4.0 mgL, 5.0 mgL and 8.0 mgL 2,4-DNT for eight weeks. Both first and second order growth constants indicated reduced growth rates with increasing 2,4-DNT concentration. The threshold concentration for significant growth rate reduction was 0.05 mgL 2,4-DNT. No histological abnormalities were found in the digestive tract, pancreas, integument, heart, gonad, head kidney and spinal cord. Significant histopathological responses were observed in liver, spleen, trunk kidney, lateral line and gill in fish exposed to 0.5 mgL - 8.0 mgL 2,4-DNT for 45 - 56 days. The 2,4-DNT was rapidly absorbed 24-96 hours, reached relatively low bioconcentration levels and was rapidly eliminated 24-72 hours when fish were placed in 2,4-DNT free environment. Author
- Anatomy and Physiology
- Ammunition and Explosives