Accession Number:

ADA101346

Title:

Intestinal Colonization by Enterotoxigenic Escherichia coli.

Descriptive Note:

Rept. no.4 (Final) Sep 74-Sep 79,

Corporate Author:

IOWA STATE UNIV AMES DEPT OF PATHOLOGY

Personal Author(s):

Report Date:

1980-09-01

Pagination or Media Count:

26.0

Abstract:

Intestinal colonization and adhesion by enterotoxigenic E. coli is mediated by specific types of pili. These pili are antigenic and can be used in diagnosing enterotoxigenic E. coli infections. They are also good protective antigens. When pregnant dams are vaccinated parenterally or orally with pili on live piliated bacteria, they secrete antibodies against the pili in their milk. Neonates suckling dams so vaccinated are passively protected against fatal challenge by enterotoxigenic E. coli. Pili are also good candidate protective antigens for the development of vaccines to protect by active immunization. Author

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE