Accession Number:

ADA094879

Title:

Bacterial Motility: A Component in Experimental Pseudomonas aeruginosa Burn Wound Sepsis

Descriptive Note:

Journal article

Corporate Author:

ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX

Report Date:

1979-01-01

Pagination or Media Count:

5.0

Abstract:

Mutants which do not spread in soft agar were derived from a rat burn wound virulent strain of Pseudomonas aeruginosa. When inoculated on to rat burn wounds, these motility-altered strains had significantly reduced virulence. Control agar-spreading isolates that had undergone the same manipulations were found to have maintained virulence. Other than motility, no other parental characteristic was found to be altered. The non-spreading isolates were virulent when inoculated below the burn wound. It is concluded that motility is an important factor in experimental burn wound sepsis.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE