Bacterial Motility: A Component in Experimental Pseudomonas aeruginosa Burn Wound Sepsis
ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX
Pagination or Media Count:
Mutants which do not spread in soft agar were derived from a rat burn wound virulent strain of Pseudomonas aeruginosa. When inoculated on to rat burn wounds, these motility-altered strains had significantly reduced virulence. Control agar-spreading isolates that had undergone the same manipulations were found to have maintained virulence. Other than motility, no other parental characteristic was found to be altered. The non-spreading isolates were virulent when inoculated below the burn wound. It is concluded that motility is an important factor in experimental burn wound sepsis.
- Medicine and Medical Research