The Effect of Hyperbaric Oxygen on Certain Growth Features of Four Dermatophytes.
FRANK J SEILER RESEARCH LAB UNITED STATES AIR FORCE ACADEMY CO
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Four dermatophyte fungi, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporum gypseum, and Microsporum canis, isolated from human and animal tinea infections, were observed in vitro for macroscopic and microscopic growth characteristics at varying hyperbaric oxygen levels, and for various exposure times and intervals. All organisms were completely inhibited in oxygen at 3 atmospheres absolute. Trichophyton mentagrophytes, Microsporum gypseum, and Microsporum canis were completely inhibited for the duration of exposure to hyperbaric oxygen according to treatment tables routinely used for patients with Clostridial gas gangrene. Trichophyton tonsurans was inhibited only slightly during treatment table exposures. Overall experimental results provide a partial base for use of compression chamber therapy in treatment of tinea infections.
- Medicine and Medical Research