Accession Number:

ADA091542

Title:

The Sinusoidal Response of the Oculoverstibular System of Normal and Otolith Deficient Mice.

Descriptive Note:

Master's thesis,

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH

Personal Author(s):

Report Date:

1979-01-01

Pagination or Media Count:

74.0

Abstract:

The purpose of this research was to see if the otolith organs exert an influence upon horizontal semicircular canal induced nystagmus in response to horizontal angular acceleration. Both normal and otolith deficient mice were tested with sinusoidal inputs ranging from .02 hertz to 2 hertz. The results showed a slight difference in the phase lags of the oculovestibular systems of the normal and otolith deficient mice. The normal mice had a slightly larger phase lag at corresponding frequencies than did the otolith deficient mice. This phase lag was greatest at low frequencies, approximately ten degrees. It was concluded that the oculovestibular system in mice can be adequately compared to that system in man. That is, a second order transfer function for the semicircular canals and a lead-lag term for adaptation. It was also concluded that the otolith organs to influence semicircular canal induced nystagmus, possibly by modifying the adaptation time constant. This change in the adaptation time constant would produce results consistant with previously reported data which show a decrease in impulse induced nystagmus in otolith deficient mice. Author

Subject Categories:

  • Anatomy and Physiology
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE