Accession Number:

ADA090183

Title:

Cryopreservation of Schistosome Larvae.

Descriptive Note:

Annual rept. no. 3, 30 Sep 79-1 Oct 80,

Corporate Author:

BIOMEDICAL RESEARCH INST ROCKVILLE MD

Personal Author(s):

• Stirewalt,M. A.
• Richards,C. S.
• Sullivan,J. T.

Report Date:

1980-10-02

Pagination or Media Count:

6.0

Abstract:

Accomplishments during this report period include 1 A wide range of intraspecific genetic variations has been demonstrated in both S. mansoni and B. glabrata 17 strains of S. mansoni showing different patterns of snail infectivity, and 16 stocks of B. glabrata showing different patterns of parasite susceptibility are under study 2 Isozyme differences were demonstrated in 13 strains of S. mansoni and 5 stocks of B. glabrata studied 3 Histologic studies on a series of stocks of B. glabrata exposed to one strain of S. mansoni showed the host reaction could be active resistance, passive unsuitability, or susceptibility. Resistance is genetically dominant over unsuitability and susceptibility unsuitability, dominant over susceptibility 4 EM studies showed that in one stock of B. glabrata, with genetic accumulations of amebocytes in the atrium, the amebocytes attacked and destroyed muscle cells of the atrium, a reaction against self and 5 Molluscicidal effect of cashew nut shell extract for B. glabrata was shown to be due primarily to the triene component of anacardic acid.

Descriptors:

• *SCHISTOSOMA MANSONI
• ISOLATION
• STRAINS(BIOLOGY)
• MICE
• PRESERVATION
• IMMUNITY
• CERCARIAE
• CRYOBIOLOGY

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE