Accession Number:

ADA090038

Title:

Effect of Lysozyme on the Immune Response of Guinea Pigs to the Soluble Phase I Antigen of COXIELLA BURNETII.

Descriptive Note:

Interim rept.,

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD

Personal Author(s):

• Wachter,Ralph F.
• Briggs,G. P.

Report Date:

1980-08-27

Pagination or Media Count:

12.0

Abstract:

Pretreatment of guinea pigs with lysozyme prior to vaccination with the phase I antigen of Coxiella Burnetti enhanced antibody response and protection against challenge. An observed effect on macrophage migration suggests that the role of lysozyme includes stimulation of cell-mediated immunity. Author

Descriptors:

• *IMMUNITY
• *VACCINES
• ANTIBODIES
• RESPONSE(BIOLOGY)
• ANTIGENS
• GUINEA PIGS
• COXIELLA BURNETII

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE