Accession Number:

ADA083993

Title:

Effect of Microwaves on the Immune System.

Descriptive Note:

Final rept. Mar 78-Nov 79,

Corporate Author:

GEORGETOWN UNIV WASHINGTON D C DEPT OF PEDIATRICS

Report Date:

1980-03-01

Pagination or Media Count:

8.0

Abstract:

Microwave irradiation is an increasingly important environmental factor for both military and civilian populations. Because of numerous practical applications of MW, its use is widespread. Despite its immune system. Over the past year, we have been involved in evaluating particular reference to lymphocyte bearing complement receptors CR. Initial studies established threshold requirements for changing the frequency of CR spleen cells with respect to intensity, wave length, duration and cumulative effect using a mouse model. Further, genetic factors were found to play a role in predisposing these animals to the effects of MW. We have expanded the observations of the MW effect on CR cells, initiated studies of other cells of the immune system and begun to genetically map these effects. In addition to the observed effect on CR cells of the spleen as we previously observed, we have now established CR cells increased in peripheral blood and lymphoid organs, but not in bone marrow cells. During the course of these investigations, it has been found that a number of other cell populations besides those carrying complement receptors are affected by MW exposure. For example, cells bearing Fc receptors are increased, natural killer cells are increased, and myeloid progenitor cells are affected by exposure to MW.

Subject Categories:

  • Medicine and Medical Research
  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE