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Respiratory Adaptations in Acid-base Disturbances: Role of Cerebral Fluids,
ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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The respiratory and metabolic components of acid-base homeostasis are defined. A quantitative empirical description of the incomplete mutual compensations in steady acid-base disturbances primarily occurring in either of the two components is presented, based upon data compiled from the literature. Respiratory adaptations in steady acid-base disturbances of metabolic origin hyperventilation with hypocapnia in primary metabolic acidosis, and hypoventilation with hypercapnia in metabolic alkalosis are analyzed as a function of the acidity of the cerebral fluids cerebrospinal and cerebral interstitial fluid. Author
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