Accession Number:

ADA071917

Title:

Behavioral Effects of Benactyzine on Equilibrium Maintenance and a Multiple Response Task.

Descriptive Note:

Interim rept. Jan-Sep 78,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX

Report Date:

1979-06-01

Pagination or Media Count:

27.0

Abstract:

Four Macaca mulatta were tested for performance changes following exposure to benactyzine at 4 doses ranging from 0.054 mgkg to 1.7 mgkg. Performance tests included adjusted root mean square error scores obtained from the USAFSAM Primate Equilibrium Platform, and response time scores obtained from the Multiple Alternative Response Task apparatus. Dose response curves were obtained using these performance measures. It was concluded that 0.054 mgkg was near a performance sign-free dose in the Macaca mulatta. Disruptive performance can be expected at 1.7 mgkg of benactyzine in this species. Author

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE