Studies on Typhus and Spotted Fever
Annual progress rept. 1 Jul 1977-30 Jun 1978
MARYLAND UNIV COLLEGE PARK DEPT OF MICROBIOLOGY
Pagination or Media Count:
Rickettsial preparations were enriched for viability by density gradient centrifugation. The genome size of typhus group rickettsiae, Rochalimaea quintana, Bakers vole agent and R. rickettsii was found to be about 1 x 10 to 9th daltons. Hybridization techniques verified clusters of strains of R. mooseri but that the two groups were clearly different from each other and from R. rickettsii and Rochalimaea quintana. Bakers vole agent, suggested by others to be a strain of R. quintana, was found to be distinct by DNA homology and SDS-PAGE profiles of proteins.
- Medicine and Medical Research