Accession Number:

ADA065733

Title:

A Sequential Clinical Trial for Testing p1 = p2.

Descriptive Note:

Technical rept.,

Corporate Author:

STANFORD UNIV CALIF DEPT OF STATISTICS

Personal Author(s):

Report Date:

1979-02-02

Pagination or Media Count:

38.0

Abstract:

Sequential designs are proposed for clinical trials to compare two binomial success probabilities, p1 and p2. Approximations to the operating characteristics and expected sample size are obtained and compared with simulations. Special reference is made to the problem of comparing vasopressin and placebo for stopping upper gastrointestinal hemorrhage. Author

Subject Categories:

  • Pharmacology
  • Statistics and Probability

Distribution Statement:

APPROVED FOR PUBLIC RELEASE