A Sequential Clinical Trial for Testing p1 = p2.
STANFORD UNIV CALIF DEPT OF STATISTICS
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Sequential designs are proposed for clinical trials to compare two binomial success probabilities, p1 and p2. Approximations to the operating characteristics and expected sample size are obtained and compared with simulations. Special reference is made to the problem of comparing vasopressin and placebo for stopping upper gastrointestinal hemorrhage. Author
- Statistics and Probability