Hematologic Effects in Mice Exposed to Pulsed and CW Microwaves.
BATTELLE PACIFIC NORTHWEST LABS RICHLAND WASH BIOLOGY DEPT
Pagination or Media Count:
Mice were exposed in the far field of an anechoic chamber to 2880-MHz pulsed microwaves 2.3-microsec pulses, 100sec 3-7.5 hr daily for 60-360 hr. In two of five studies with 5-mWsq cm pulsed microwaves there was a significant increase in bone marrow cellularity compared to the sham-exposed groups, but in the other three exposures at 5-mWsq cm no significant effect was observed. Significant differences were occasionally seen in erythrocyte, leukocyte and platelet measurements from microwave-exposed groups, but were not consistently observed. The only effect seen in mice exposed to 5-mWsq cm CW microwaves was a reduction in reticulocyte concentrations P less than 0.02. In one of four exposures at 10-mWsq cm pulsed microwaves, mean bone marrow cellularity was reduced P less than 0.02 in the microwave-exposed mice, and in another group the concentration of circulating lymphocytes was increased P less than 0.05. In only one exposure 10-mWsq cm for 360 hr was any effect noted on serum proteins a reduction P less than 0.02 to 5.1 or - 0.29 gdl in the exposed vs 5.6 or - 0.36 gdl in the sham-exposed mice. This was due to a decrease in alpha and beta-globulins, with no effect on albumin or gamma-globulin concentrations. No effect on bone marrow hematopoietic colony-forming units CFU was revealed by CFU-agar assay techniques following exposure of mice to 5-mWsq cm pulsed microwaves. In 1 of 4 exposures of mice to 10-mWsq cm pulsed microwaves there was a significant P less than 0.05 increase in CFU-agar colonies.