Accession Number:

ADA064949

Title:

Mutagen and Oncogen Study on Nitroguanidine

Descriptive Note:

Final rept.

Corporate Author:

LITTON BIONETICS INC KENSINGTON MD

Personal Author(s):

Report Date:

1978-09-01

Pagination or Media Count:

59.0

Abstract:

The material evaluated in this study was subjected to a matrix of in vitro assays employing microbial cells, mammalian cells in culture and in vivo tests measuring potential germ cell effects in mice and rats. Nitroguanidine produced no evidence of genetic activity in any of the studies comprising this investigation. No evidence for genetic potential or risk was obtained under the conditions of this evaluation. No evidence for genetic potential or risk was obtained under the conditions of this evaluation.

Subject Categories:

  • Medicine and Medical Research
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE