Synchronized Pulsatile Extracorporeal Coronary Perfusion: Its Effects on Preservation of Left Ventricular Function in the Beating Nonworking Canine Heart.
Pilot study rept. 1975-1976,
LETTERMAN ARMY INST OF RESEARCH SAN FRANCISCO CALIF
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Twelve mongrel dogs were divided into two groups and subjected to either continuous or synchronized pulsatile cardiopulmonary bypass. Left ventricular function was evaluated with measurements of stroke volume, stroke work, and dpdt maximum. Although slight reductions were noted in the values for stroke volume and stroke work following two hours of left ventricular bypass in both groups, no significant effects attributable to perfusion modality were noted. The results of this study suggest that in the beating nonworking canine heart synchronized pulsatile perfusion offers no advantage over standard continuous cardiopulmonary perfusion. Author
- Anatomy and Physiology