Accession Number:

ADA063119

Title:

Transmission, Control and Treatment of Infectious Diseases of Military Importance in Equatorial Asia.

Descriptive Note:

Annual rept. 1 Oct 74-30 Sep 75,

Corporate Author:

INSTITUTE FOR MEDICAL RESEARCH KUALA LUMPUR (MALAYSIA)

Report Date:

1975-01-01

Pagination or Media Count:

37.0

Abstract:

Local and foreign populations have been found which are sustaining significant infections with R. tsutsugamushi. Rodent hosts of the common vector chiggers have been trapped in the areas where several of the populations are exposed to the disease. Rickettsial isolations have been achieved from humans, rodents, and chiggers and the strains are being identified. A micro-IFA test which produces equivalent data in a shorter period of time with a saving in reagents has been developed. Passively transferred convalescent sera do not completely protect mice against challenge with homologous scrub typhus strains and are ineffective against heterologous strains. L. L. fletcheri and L. L. arenicola chigger colonies infected with R. tsutsugamushi have been employed to study the effects of the duration of feeding and ambient temperature on transmission of organism. Samples have been shipped to WRAIR to examine the ultrastructure of organism in the vector and the fate of the rickettsia following attempted infections. Author

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE