Synthesis of Some 6-Aralkyl-2, 4-Diamino-5,6,7,8-Tetrahydropyrimido (4,5-d) Pyrimidines.
Annual rept. n0. 2, Oct 77-Aug 78,
CENTRAL MICHIGAN UNIV MOUNT PLEASANT
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Exploratory investigations in several series of amines were conducted with the view of obtaining optimum conditions as well as representatives examples for biological screening. Difficulties encountered with either the reactivity of some of the amines or the stability of some of the products prevented completion of this initial goal. Where such areas of difficulty arose further work will be required. A series of 6-substituted benzyl-2,4-diamino-5,6,7,8-tetra-hydropyrimido 4,5-d pyrimidines has been prepared and is in the process of being submitted for screening. Author
- Organic Chemistry