Genetics of Novel Hybrid Bacteriophage and Development of Generalized Transducing System for 'Salmonella typhosa.'
Annual progress rept. no. 5, 1 Jan-31 Aug 78,
TEMPLE UNIV PHILADELPHIA PA SCHOOL OF MEDICINE
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We mapped the phage chromosomes of hybrids between Salmonella phage P22 and coliphages. Since the genomes of hybrid phages consist of clusters of genes derived from evolutionary diverse bacteriophages, we studied the physical length of the homology between parental phages and hybrid phages and controls of various gene expressions in these hybrid phages. In this progress report we show the origin of genetic segments in the hybrid phage genomes and the expression of dispensable genes such as the somatic antigen conversion gene a1 and the P22 tail component gene 9 in these hybrid phages.