Accession Number:

ADA059100

Title:

Synthesis of Rationally Designed Organic Compounds for Malaria Chemotherapy Studies.

Descriptive Note:

Annual progress rept. no. 12, 1 Aug 76-31 Jul 77,

Corporate Author:

MIDWEST RESEARCH INST KANSAS CITY MO

Personal Author(s):

Report Date:

1978-04-28

Pagination or Media Count:

46.0

Abstract:

During the present report period, 20 compound targets and intermediates of the following categories have been synthesized, characterized, and submitted for antimalarial evaluation a deazafedbrifugine, b 1,5-naphthyridines, and c 8-aminoquinolines. WR-235202 exhibited good antimalarial activity against Plasmodium berghei. Author

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE