Synthesis of Rationally Designed Organic Compounds for Malaria Chemotherapy Studies.
Annual progress rept. no. 12, 1 Aug 76-31 Jul 77,
MIDWEST RESEARCH INST KANSAS CITY MO
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During the present report period, 20 compound targets and intermediates of the following categories have been synthesized, characterized, and submitted for antimalarial evaluation a deazafedbrifugine, b 1,5-naphthyridines, and c 8-aminoquinolines. WR-235202 exhibited good antimalarial activity against Plasmodium berghei. Author