Decontamination of Combat Wounds in the Injured Soldier.
Annual rept. 1 Jan 77-31 May 78,
VIRGINIA UNIV CHARLOTTESVILLE DEPT OF PLASTIC SURGERY
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Management of traumatic injuries should be rapid and effective. This therapy should be directed towards reestablishment of normal tissue functions without any further debilitation. This report summarizes several studies on how infection may be reduced in the contaminated traumatic wound. Topical application of proteolytic enzyme solution to open wounds enhances the action of antibiotic therapy. Topical enzymes remove the surface coagulum which protects bacteria from the action of antimicrobial agents. By dissolving the coagulum the bacteria are exposed and more effectively eliminated. The enzyme treatment also allows more antibiotic to reach the site of injury. This treatment of open wounds with proteolytic enzymes does not affect wound healing or normal tissue defenses.
- Weapons Effects (Biological)