Accession Number:

ADA056019

Title:

A Literature Review - Problem Definition Studies on Selected Toxic Chemicals. Volume 2. Occupational Health and Safety Aspects of Phosphorus Smoke Compounds

Descriptive Note:

Final rept. Mar 77-Apr 78,

Corporate Author:

FRANKLIN INST RESEARCH LABS ROCKVILLE MD SCIENCE INFORMATION SERVICES DEPT

Personal Author(s):

• Wasti, Khizar
• Abaidoo, K. J. R.
• Villaume, Jon E.

Report Date:

1978-04-01

Pagination or Media Count:

104.0

Abstract:

This Problem Definition Study provides information on toxicological aspects and health hazards of phosphorus smoke compounds. The compounds covered in this study are red phosphorus, white phosphorus, butyl rubberred phosphorus, plasticized white phosphorus, and epoxy white phosphorus. The subjects covered in this review are chemical and physical properties, toxicity, pharmocokinetics, sampling and analysis, industrial hygiene and safety practices, and standards. Recommendations for further toxicological studies on animals are also provided. There is virtually no information on the toxicity of butyl rubberred phosphorus, plasticized white phosphorus, or epoxy white phosphorus. The toxicity of red phosphorus has not been studied very well. White phosphorus has been found to be highly toxic to both experimental animals and humans. Occupational exposure to white phosphorus vapors has produced necrosis of the jaw phossy jaw among workers. There have been no reported cases of carcinogenicity in humans after white phosphorus intoxication. Tests for mutagenicity and teratogenicity have not been reported in the literature. Author

Descriptors:

• *TOXICITY
• *SMOKE MUNITIONS
• *PHOSPHORUS COMPOUNDS
• LITERATURE SURVEYS
• HUMANS
• CHEMICAL PROPERTIES
• PHYSICAL PROPERTIES
• HEALTH
• SAMPLING
• SAFETY
• PHARMACOKINETICS
• LABORATORY ANIMALS
• INHALATION
• WHITE PHOSPHORUS

Subject Categories:

• Toxicology
• Pyrotechnics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE