Neuropsychological Studies of Alcohol.
Final rept. 1 Jul 73-30 Apr 76,
CALIFORNIA UNIV SAN FRANCISCO DEPT OF PSYCHIATRY
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A series of four studies were conducted on highly practiced male volunteer subjects to investigate the relationship of electroencephalographic EEG parameters to alcohol-induced performance changes under conditions of low and high motivation and stress. The nature of the EEG-performance association varied with the experimental conditions and was observed primarily when the subject was under high levels of alcohol or was highly stressed or motivated. EEG activation increased when fast performance occurred during a state of high alcohol. Without the state of high alcohol, fast performance was related to decreased EEG activation. The combination of alcohol and sleep deprivation produced interaction effects that varied from antagonistic to synergistic depending on the response measure. From these data it was concluded that the best strategy for looking at EEG-performance relationships is to put a load on the system either in the form of a handicap high alcohol or stress. To look for EEG correlates of good and bad performance when the system is in normal condition would seem to require other than scalp EEG. Author