Principles and Procedures for Evaluating the Toxicity of Household Substances.
NATIONAL RESEARCH COUNCIL WASHINGTON DC COMMITTEE ON TOXICOLOGY
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This useful information resource updates and expands on information presented in the widely read 1964 report published under the same title. In it you will find discussions in the following areas 1 the methodologies for administering chemicals for acute and subchronic studies 2 types of tests commonly used to assess acute hazards of chemicals to skin and eyes 3 guidelines for the conduct of inhalation toxicity assessment 4 the principles involved in the design and interpretation of chronic toxicitycarcinogenicity studies 5 assay systems for detecting heritable genetic damage and the assessment of mutagenic hazard by progression from simple to more complex test systems 6 tests to assess reproductive toxicity, including birth defects and 7 a research strategy and methodology for the study of agents suspected of influencing the central nervous system and causing alterations in either general or operant behavior. Author