Accession Number:
ADA052694
Title:
Oxazinediones and Related Compounds as Antimalarial Agents.
Descriptive Note:
Final rept. 1974-1976,
Corporate Author:
TEMPLE UNIV PHILADELPHIA PA
Personal Author(s):
Report Date:
1978-04-04
Pagination or Media Count:
87.0
Abstract:
Objective- To develop new chemical agents for the treatment of malaria and related parasitic diseases by preparing samples of new organic compounds for testing against murine malaria. Rationale- Because simple derivatives of compounds containing the oxazinedione ring system were known to exhibit inhibitory activity in E. coli. and other microorganisms, it was hoped that a systematically prepared group of derivatives of oxazinediones would include compounds of activity against Plasmodia.
Descriptors:
Subject Categories:
- Pharmacology
- Organic Chemistry