Accession Number:

ADA052002

Title:

Methods for Teratogenic Screening of Air Force Chemicals

Descriptive Note:

Technical rept. Aug-Oct 1977

Corporate Author:

AIR FORCE AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OH

Personal Author(s):

Report Date:

1978-01-01

Pagination or Media Count:

9.0

Abstract:

The Fisher 344 strain of rat is commonly used in this Laboratory, especially for oncogenicity studies. To determine the suitability of the Fisher 344 strain of rat for teratogenicity studies and to gain experience in the procedures, pregnant Fisher 344 rats were exposed to two dose levels of hydroxyurea, a cancer chemotherapeutic drug and a known teratogen.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE