Accession Number:

ADA051730

Title:

Change in Phagocytic Activity to Tularemia Microbe in Highly Sensitive Animals with Mixed Infection,

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD

Personal Author(s):

Report Date:

1978-03-17

Pagination or Media Count:

13.0

Abstract:

An increase of the ingestive and digestive capacity of neutrophils to the homologous causative agent and tularemia microbe was revealed by the opsonophagocytic test in Microtus arvalis, albino mice and guinea pigs infected with sublethal Yersinia pseudotuberculosis and Salmonella typhimurium doses. In subsequent tularemia infection some of the animals displayed a reduction of the septicemia intensity, prolongation of the disease and elevation of the surceptibility threshold. Period of manifestation of the inhibitory action on tularemia coincide with that of the increase in phagocytic activity. Author

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE