Accession Number:

ADA050057

Title:

Biological Applications and Effects of Optical Masers.

Descriptive Note:

Progress rept. no. 677, 1 Sep 76-31 Aug 77,

Corporate Author:

MEDICAL COLL OF VIRGINIA RICHMOND HEALTH SCIENCES DIV

Report Date:

1976-06-01

Pagination or Media Count:

25.0

Abstract:

The pathology of photochemical lesions of the rhesus retina resulting from extended exposure 1000 s to blue light 441nm as investigated with light and electron microscopy is described in detail for periods post-exposure ranging from one hour to ninety days. This photopathology correlates well with visual acuity performance in trained rhesus monkeys. The new 2500 W Xenon lamp system with quartz optics is described along with its capabilities for providing exposures in the near infrared, visible and near ultraviolet spectral regions. Preliminary data on 1000 eight ms pulses of 441 nm light at a one pulse per second repetition rate indicate that the radiant exposure required to produce a threshold lesion is lower than for cw exposure. Some preliminary exposures of the retina of aphakic monkeys support the thesis that the retina is quite sensitive to near ultraviolet damage. Also, repetitive exposures to blue light show that cumulative damage can occur in the retina. Author

Subject Categories:

  • Radiobiology
  • Lasers and Masers

Distribution Statement:

APPROVED FOR PUBLIC RELEASE