Accession Number:

ADA048027

Title:

The Accuracy of Curve Fitting Procedures for the Determination of the Rate Constant for Reactivation of an Acylated Esterase,

Descriptive Note:

Corporate Author:

MATERIALS RESEARCH LABS ASCOT VALE (AUSTRALIA)

Report Date:

1977-07-01

Pagination or Media Count:

23.0

Abstract:

Curve fitting procedures were examined for determination of the three unknown parameters A, B and k in the equation y A-Be-kt. Six methods were evaluated one based on the sum of differences, three based on the sum of squares, and two based on the sum of squares for the equation in a linear form. It was concluded that no method was satisfactory. Even when an apparently accurate estimate of the rate constant k was obtained, it was accompanied by wide confidence limits. If possible, the constant A should be determined independently satisfactory results can then be obtained. Author

Subject Categories:

  • Biochemistry
  • Theoretical Mathematics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE