Inactivation of Enkephalins: Effect of Purified Peptidyl Dipeptidase and Cultured Human Endothelial Cells.
TEXAS UNIV HEALTH SCIENCE CENTER AT DALLAS
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Cultured human endothelial cells inactivate enkephalins primarily by the action of an aminopeptidase, as demonstrated by the release of TYR1. In addition a purified peptidyl dipeptidase cleaved enkephalins to tri- and dipeptide. Author