The Effects of Acute Alterations in Hemodynamics, Oxygen Availability and Acid-Base Balance on the Permeability of the Gastric Mucosa.
Annual progress rept. 1 Oct 75-30 Sep 76,
VIRGINIA UNIV CHARLOTTESVILLE SCHOOL OF MEDICINE
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Using a previously described model for acute gastric mucosal ulcerogenesis Gastroent. 68 699, 1975, studies indicated that the glycine conjugates of cholic acid possesses a potential for ulcerogenesis equal to that of the taurine conjugates that acute ulcerogenesis is associated with a significant reduction in gastric mucosal ATP content and that the severity of mucosal injury under these circumstances is bile acid concentration dependent.
- Anatomy and Physiology