Accession Number:

ADA046614

Title:

The Effects of Acute Alterations in Hemodynamics, Oxygen Availability and Acid-Base Balance on the Permeability of the Gastric Mucosa.

Descriptive Note:

Annual progress rept. 1 Oct 75-30 Sep 76,

Corporate Author:

VIRGINIA UNIV CHARLOTTESVILLE SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1976-07-20

Pagination or Media Count:

7.0

Abstract:

Using a previously described model for acute gastric mucosal ulcerogenesis Gastroent. 68 699, 1975, studies indicated that the glycine conjugates of cholic acid possesses a potential for ulcerogenesis equal to that of the taurine conjugates that acute ulcerogenesis is associated with a significant reduction in gastric mucosal ATP content and that the severity of mucosal injury under these circumstances is bile acid concentration dependent.

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE