Accession Number:

ADA046319

Title:

Physiology and Metabolism of 'Neisseria gonorrhoeae'.

Descriptive Note:

Final rept. 1 Jul 74-30 Jun 76,

Corporate Author:

OREGON UNIV HEALTH SCIENCES CENTER PORTLAND DEPT OF MICROBIOLOGY AND IMMUNOLOGY

Personal Author(s):

Report Date:

1976-12-01

Pagination or Media Count:

49.0

Abstract:

The principal findings have been 1 The respiratory chain appears to contain several nonheme iron centers, cytochrome c, two b cytochromes, with cytochrome o which probably serves as the terminal oxidase. 2 Acetate accumulates during glucose catabolism and is not further metabolized until glucose catabolism ceases. Then, acetate is oxidized by the tricarboxylic acid cycle TCA cycle. 3 Although acetate does not enter the TCA cycle during glucose catabolism, a portion of the cycle functions as evidenced by the oxidation of glutamate. 4 The gonococcus does not contain a pyridine nucleotide-dependent malate dehydrogenase. Instead, this organism possesses a FAD-dependent malate oxidase which appears to be associated with the electron transport chain. 5 A rapid method was developed to identify Neisseria spp. by the production of acid from specific carbohydrates.

Subject Categories:

  • Biochemistry
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE