Physiology and Metabolism of 'Neisseria gonorrhoeae'.
Final rept. 1 Jul 74-30 Jun 76,
OREGON UNIV HEALTH SCIENCES CENTER PORTLAND DEPT OF MICROBIOLOGY AND IMMUNOLOGY
Pagination or Media Count:
The principal findings have been 1 The respiratory chain appears to contain several nonheme iron centers, cytochrome c, two b cytochromes, with cytochrome o which probably serves as the terminal oxidase. 2 Acetate accumulates during glucose catabolism and is not further metabolized until glucose catabolism ceases. Then, acetate is oxidized by the tricarboxylic acid cycle TCA cycle. 3 Although acetate does not enter the TCA cycle during glucose catabolism, a portion of the cycle functions as evidenced by the oxidation of glutamate. 4 The gonococcus does not contain a pyridine nucleotide-dependent malate dehydrogenase. Instead, this organism possesses a FAD-dependent malate oxidase which appears to be associated with the electron transport chain. 5 A rapid method was developed to identify Neisseria spp. by the production of acid from specific carbohydrates.