Accession Number:

ADA045411

Title:

A Diffusion Approximation Analysis of a General n-Compartment System.

Descriptive Note:

Interim technical rept.,

Corporate Author:

CARNEGIE-MELLON UNIV PITTSBURGH PA DEPT OF STATISTICS

Personal Author(s):

Report Date:

1977-05-01

Pagination or Media Count:

42.0

Abstract:

A new approach to the stochastic analysis of general compartment models is presented. The analysis is based on the concept of diffusion approximations. The state of a compartment system is represented as the superposition of a deterministic process, characterized by a system of ordinary differential equations, and a random noise process characterized by stochastic differential equations. All transition rate parameters are permitted to be time dependent. Numerical solutions are presented for the two-compartment case, and compared with those of Cardenas and Mates 1975a. Extensions to non-linear compartment models are discussed. Author

Subject Categories:

  • Pharmacology
  • Statistics and Probability

Distribution Statement:

APPROVED FOR PUBLIC RELEASE