Accession Number:

ADA043042

Title:

An Animal Model to Predict Aggressive Behavior Produced by the Withdrawal from or Abuse of Drugs.

Descriptive Note:

Final rept. 1 Jul 73-1 Jan 75,

Corporate Author:

CALIFORNIA UNIV SAN FRANCISCO DEPT OF PSYCHIATRY

Personal Author(s):

Report Date:

1976-03-23

Pagination or Media Count:

52.0

Abstract:

The research conducted under this contract indicated that the hamster is a useful animal to study withdrawal from opiates and the agonistic behavior that ensues. This behavior may not be taxonomically related to more natural forms of aggression, but seems to be closely related to aversive internal stimulation produced by withdrawal. The social context within which aggression is expressed is most important and morphine withdrawal while not directly affecting agonistic behavior may indirectly do so by producing changes in the social structure. Dopaminergic mechanisms may mediate this agonistic behavior by increasing activity. Author

Subject Categories:

  • Psychology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE